Job added in hotlist
Applied job
Contract job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Bedford, MA
View more jobs in Massachusetts

Job Details

Sr Research Associate Cloning /Molecular Biology

Bedford, MA

Apply for this job


Research Associate /Sr Research Associate – Cloning /Molecular Biology
Job Code : CMBRA-0027-18
Location: Bedford, MA
We are seeking a Research Associate/Sr Research Associate for the Drug Discovery Biology Group at **MEMBERS ONLY**SIGN UP NOW***.. The individual will be energetic, self-motivated with a desire to succeed at the highest level, joining a team of scientists aiming to develop unique AAV/Gene Editing technology for targeted gene therapy indications. The individual will interact with other team members to design and execute advanced cloning technology to support on going molecular and cell biology experiments aimed at developing effective vector designs for appropriate biological targets. Significant cross-functional collaboration with a talented and dedicated group of scientists including molecular biologists, cell biologists, bioinformaticians and virologists will ensure a diverse exposure to the drug discovery process. As part of the team the candidate will have significant responsibility to drive success of their own project with opportunities to acquire new skills in an innovative and fast-paced environment. The position offers the opportunity to leverage our unique technology in early discovery projects and play a crucial role in the rapid translation to both pre-clinical and clinical settings.
Principal Duties and Responsibilities
Developing, optimizing and performing advanced cloning and genomic construction techniques to enable the characterization of the mechanism of action of HMI’s proprietary AAV gene editing technology.
Use advance cloning techniques such as Gateway, Golden Gate and Gibson Assembly in a medium and high throughput applications.
Work with the latest gene editing software packages (SnapGene / Vector NTI ) to assist in sequence analysis, and genomic predictions
Perform laboratory experiments and report data and suggest future work to management and project teams
Design and excecute a variety of mammalian cell based assays to confirm and evaluate both gene expression and gene editing vector designs.
Maintenance of electronic laboratory notebook including accurate and detailed recording of methods, resuls, data analysis, and conclusions
BS/MS or equivalent;
2-4+ years of industrial/academic laboratory experience
Proven ability to work independently and design experiments, trouble shoot, interpret and report data back to teams
Proficiency in cutting edge molecular techniques including Gibson assembly, large and small scale plasmid purification, DNA sequencing/analysis, and working knowledge of advanced molecular techniques and concepts
Experience with cell biology including maintenance of mammalian cell cultures, transient plasmid transfection, and Western blotting.
Familiarity with medium and high-throughput cell & molecular based assays and knowledge of AAV gene therapy a plus
Knowledge of DNA analysis software (SnapGene, Vector NTI, Geneious, Sequencher or similar)
Highly analytical mind, attention to detail, and organization skills are critical
Collaborative and proactive attitude
Excellent written and oral communication skills
Interested candidates should forward a cover letter and Resume / CV to
******MEMBERS ONLY**SIGN UP NOW***., Inc. (HMI) has built foundational intellectual property on gene editing and gene therapy vectors derived from naturally occurring human adeno-associated viruses (AAVs). The Company's technology is precise, on-target and highly efficient for in vivo editing of genetic mutations. This transformative platform technology, combined with an elite leadership team of biopharmaceutical industry veterans, create a significant opportunity for HMI to rapidly advance a diverse pipeline of new medicines that address and potentially cure the underlying cause of genetic diseases
Job Type: Full-time

Company info

Sign Up Now -

Similar Jobs:
Job Description: Job Description Job Summary Job Title: Director, Early Stage Process Development/Gene Therapy Reports To: Sr. Director, Gene Therapy Process Development Location: Andover, MA The Co...
Job Description: Job Description The Company: Sarepta Therapeutics is a commercial-stage biopharmaceutical company focused on the discovery and development of precision genetic medicines to treat rare neuromuscular diseases. The C...
Job Description: Responsibilities include to perform duties related to system support and maintenance, provides technical support service, repairs and preventive maintenance as necessary to maintain the safe operation of BWH's bio...
I was facing the seven-year itch at my previous workplace. Thanks to EmploymentCrossing, I'm committed to a fantastic sales job in downtown Manhattan.
Joseph L - New York, NY
  • All we do is research jobs.
  • Our team of researchers, programmers, and analysts find you jobs from over 1,000 career pages and other sources
  • Our members get more interviews and jobs than people who use "public job boards"
Shoot for the moon. Even if you miss it, you will land among the stars.
BiotechCrossing - #1 Job Aggregation and Private Job-Opening Research Service — The Most Quality Jobs Anywhere
BiotechCrossing is the first job consolidation service in the employment industry to seek to include every job that exists in the world.
Copyright © 2018 BiotechCrossing - All rights reserved. 168