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Job Details

Postdoctoral Research Fellow Immunopeptidomics amp Chemical Biology Proteomics

Company name
Merck & Co., Inc

Boston, MA, United States

Employment Type

Biotech, Sciences, Research, Post Doc, Pharmaceutical

Posted on
Jan 04,2019

Valid Through
Apr 19,2019

Apply for this job


Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its

legacy for over a century

. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

Be a part of the legacy: MRL Postdoctoral Research Fellow Program

The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

As a Postdoctoral Fellow in the Chemical Biology Chemoproteomics group based in Boston, MA, you will work with an interdisciplinary and highly collaborative team of scientists to design and implement novel chemical, analytical, and biological methods for investigating antigen presentation, primarily through proteomic technologies. This work will enable understanding of antigen presentation biology and improve capabilities for cancer neoantigen discovery towards development of oncology vaccines.

Responsibilities include but are not limited to:

Developing and optimizing innovative biochemical and proteomic workflows.

Establishing tumor models to evaluate immunopeptidome modulation.

Bioinformatic analysis of deep datasets.

Presentation and publication of experimental results.



Education Minimum Requirement:

A PhD with less than (3) years of postdoctoral experience OR graduating with a PhD by summer of 2019.

Required Experience and Skills:

Experience in common tissue culture techniques.

Experience and working knowledge of biochemistry and molecular biology techniques including Western blotting, immunoaffinity precipitation (IP), and transfection.

Ability to learn and operate independently.

History of publication in peer-reviewed journals.

Preferred Experience and Skills:

Background in cellular immunology or the application of proteomics or peptidomics for immunology research.

Hands-on experience in mass spectrometry is beneficial but not necessary.

Working knowledge of bioinformatic tools; preferably experience with R or a scripting language.

Experience in culturing primary cells, organoids, or other 3D culture systems.

Knowledge of chemical biology approaches and their applications.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement

OFCCP EEO Supplement

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of it’s manifestations.


Post-Doctoral Fellow

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Company info

Merck & Co., Inc
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Company Profile
Merck has a long and rich history of working to improve people's health and well-being. Through the years, our researchers have helped to find new ways to treat and prevent illness - from the discovery of vitamin B1, to the first measles vaccine, to cold remedies and antacids, to the first statins to treat high cholesterol. Our scientists also have helped develop many products to improve animal health, including vaccines and antibiotics. While we are proud of our past, we are enthusiastic about the future of this new company and we are excited to help create a healthier, brighter future for people around the world.

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