Scientist - Biomarker Development

Profile

The Position

We are seeking a highly motivated Scientist to join the OMNI-Biomarker Development Department within Development Sciences to drive our biomarker and drug development efforts in immunology and respiratory diseases. Our department is responsible for defining biomarker and personalized healthcare strategies, designing and implementing biomarker assays in clinical trials, and interpreting biomarker results. Our group uses relevant biomarkers to evaluate disease heterogeneity, target-engagement, mechanism of action, and disease modification; and to guide clinical diagnostic biomarker development. Biomarker team leaders within the department provide scientific leadership for biomarkers in clinical trials ranging from early proof-of-concept through marketed products.

Responsibilities:

The successful candidate will join our dynamic team and work to identify and develop biomarkers in support of drug development projects targeted for treatment of immunology and respiratory diseases. The candidate will support novel therapeutic candidates before and after transition from research through all phases of clinical development via close collaboration with research scientists and development functions. The successful Scientist will have the opportunity to grow into a project biomarker team leader and manager of a lab-based team. Success in these responsibilities requires a thorough understanding of disease and drug target biology, creativity and attention to detail, and experience in integrating biomarkers into clinical trials. Candidates familiar with molecular/immunological techniques and methods including immunoassays, cytometry, transcriptomics, genetics, cellular immunology, and infectious assays will be given preference. The position requires working in close partnership across various functions including Research, Bioanalytical Assay Department, Diagnostics, Clinical Sciences, Biostatistics, Bioinformatics, Regulatory, and with external partners. Effective communication is essential and includes presentations at cross-functional teams, internal review committees, and external conferences, and will also involve writing biomarker sections of clinical protocols, reports, regulatory filings and scientific publications.

Who You Are

Candidates must have a PhD or MD in a field of immunology or a related field with at least 3 to 5 years of post-doctoral or fellowship experience in basic or translational research either in an academic and/or industry setting. The candidate must demonstrate a high level of independence and be able to develop hypotheses and direct analysis plans. Strong writing and communication skills are required, as evidenced by publications, meeting abstracts and/or drug development reports. We are looking for an individual who would be passionate about using their understanding of disease biology to make impactful contributions to clinical drug development. Preferred candidates will have prior experience with immune related diseases, human samples, and a demonstrated ability to function as part of a cross-functional team such as research or clinical trial project teams

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Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page

Company info

Genentech, Inc.
Website : http://www.gene.com