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Associate Scientist/Scientist Drug Metabolism and Pharmacokinetics Genentech Research

San Francisco, CA

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Genentech: Associate Scientist/Scientist, Drug Metabolism and Pharmacokinetics, Genentech Research
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Associate Scientist/Scientist, Drug Metabolism and Pharmacokinetics, Genentech Research
South San Francisco
California, United States of America
Job ID: 3599458958
The Position
The department of Drug Metabolism and Pharmacokinetics (DMPK) at Genentech is seeking an exceptional candidate to support in silico ADME, guide DMPK SAR and influence chemical design. The candidate will build, apply and maintain in silico ADME models and tools to support discovery project teams. S/he will work with our established team to exploit and expand the existing modeling suite using state of the art computational chemistry and cheminformatics approaches (e.g. machine learning QSAR, matched molecular pairs, structure based design). Additionally s/he'll focus on predictive ADME and early Physiologically-Based PK models, linking in silico, in vitro and in vivo in a semi-automated fashion to inform molecular lead optimization via early human PK prediction. As part of the DMPK team s/he will explore ADME SAR, in vitro to in vivo correlations, leverage in silico and in vitro data to guide next steps for generating and testing experimental hypothesis as well as aid compound design. A key part of the role will be continuing education, both within DMPK and the small molecule organization, about predictive DMPK and championing the use of in silico tools. The candidate will be a highly effective and energizing collaborator and will work with scientists from multiple disciplines beyond DMPK including computational and medicinal chemistry, biochemical pharmacology, safety assessment and pharmaceutical sciences.
Who We Are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
The next step is yours. To apply today, click on the Apply online button.
Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our .
At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.
Job Facts
Job Function
South San Francisco
California, United States of America
Full time
Job type
Biotechnology / Science
Previous Job:
Home Depot
Atlanta, GA
Next Job:
Postdoctoral Research Fellow, Genomics and Bioinformatics, Manning lab, Genentech Research
South San Francisco of America

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