Job added in hotlist
Applied job
Contract job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Boston, MA
View more jobs in Massachusetts

Job Details

Associate Director Translational Genomics amp Genetics Lead

Company name
Takeda Pharmaceutical Company Limited.

Boston, MA, United States

Employment Type

Manager, Biotech, Sciences

Posted on
Oct 05, 2021

Valid Through
Jan 18, 2022

Apply for this job


Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Associate Director, Translational Genomics and Genetics Lead in our Cambridge, MA or San Diego, CA offices.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future

to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.


This position requires an acknowledged technical and strategic expert whose primary role is to provide genomics and genetic leadership, research planning and decision making in assigned Gastroenterology, Hepatology, Neurogastroenterology, and Motility disease projects in the preclinical and clinical stages.

This is a highly visible and matrixed role, responsible for

partnering with Gastro-Intestinal drug discovery unit (GI-DDU) Discovery Research scientists, Translational Biomarker Research leads, Physician Scientists, Biostatisticians, and Computational Biologists and work in project teams to define program strategy for transcriptomics, genomics, pharmacogenomics, and genetics relevant to patients in clinical studies. Work closely with functional line leadership to develop Genomics and Genetics plans as part of the overall Asset Strategy in the Global Product Teams through all stages of Research, clinical development, and post-market activities.


Partner with GI-DDU Discovery Research Leads, Translational Biomarker Leads and Physician Scientists in defining and executing fit-for-purpose transcriptomics, genomics, pharmacogenomics, and genetics strategies for translational studies in targeted pathways in the discovery research stages and define candidate gene polymorphisms, and transcriptomics gene sets to be used for patient selection, as surrogates of drug efficacy, understand drug mechanism of action, and safety.

Lead Translational Genomics and Genetics strategy development and execution to support the clinical stage portfolio, including the biomarker driven clinical studies, implementation of novel technologies and incorporation of biomarker endpoints for decision making in early-stage clinical trials.

Collaborate across multiple sites and functional areas, working closely with Translational Biomarker Leads, Physician Scientists, Discovery Research scientists, Clinical Study Leads, Statistical Genetics, Bioinformatics and Computational Biologists and nonclinical colleagues build consensus for a fit-for-purpose Translational Genomics and Genetics strategy

As a subject-matter expert, collaborate with Translational Biomarkers Research Lead on Project and Global Product Teams to provide Translational Genomics and Genetics strategy to support translational medicine goals for progression of program from discovery research through clinical development and to support overall asset strategies

Evaluate and utilize state-of-the-art scientific tools and implement cutting-edge technology to drive innovation in the fit-for-purpose validation and execution of transcriptomics, genomics, pharmacogenomics, and genetics assays, data reporting and visualization platforms, ensuring high scientific quality

Participate in large academic/industry partnerships/consortia and leverage data from large biobanks (including UK Biobank; IBD-Plexus; Crohn’s and Colitis Foundation; FNIH) to support GI-DDU programs

Responsible for the preparation and review of transcriptomics, genomics, pharmacogenomics, and genetics sections of candidate nomination documents, clinical protocols and documents submitted to Regulatory Agencies

Support Business Development efforts by evaluating potential in-licensing opportunities and serve as a liaison with external companies, organizations, consultants, university representatives, NIH, and with Regulatory Agencies, as required

Establish and maintain scientific dialog with KOLs and Genomics and Genetics experts in medical, academic, and regulatory communities


Outstanding expertise and depth of knowledge within transcriptomics (including next-generation sequencing-NGS), genomics, pharmacogenomics and genetics platforms for translational biomarkers applications

Collaborate with statistical genetics, bioinformatics and computational biology colleagues to integrate data from large human genetic datasets, including GWAS, RVAS, eQTL/pQTL studies, and Mendelian genetics and visualize transcriptomics TSNE, genomic data, association studies using transcriptomics, genetic and genomic data

Keeps up with the cutting-edge scientific advancement and maintain extensive knowledge of research and development efforts (e.g. competitive landscape, new technology, new research portfolio, and new partnerships)


Scientific leadership role, setting high standards for effectiveness of execution, and rigor of thought

Decision-making and Autonomy

Independently manages workload and expectations

Scientifically independent

Scientific driver for research strategy that impacts group internally and outside area of function


Initiates and leads external interactions and collaborations

Frequent contact with internal and external personnel at various management levels


Determines methods on new assignments; makes strategic recommendations on projects


(Products managed, mix of businesses, internal and/or external business environment, cultural considerations)

Operate in matrix environment providing Translational genomics and genetics expertise  on discovery and development teams


PhD or MD/PhD degree in relevant field with 8 years of experience

At least 3 years of experience in translational genomics and genetics research.

Experience in any combination of the following areas is required: transcriptomics (including NGS), genomics, pharmacogenomics, and genetics (multiple openings at different levels commensurate with experience).

Experience working with and manipulating large genomic, transcriptomics data sets and familiarity with R programming environment, AI and machine learning based models is desirable.

Recognized expertise in translational genomics and genetics discovery and development as demonstrated by publications, regulatory submissions and/or national or international presentations

Excellent understanding of drug development, regulatory processes, and clinical development

Strong leadership abilities and proven ability to lead a team within a matrix organization as well as work independently

Strong analytical, oral and written communication, problem solving and interpersonal skills


Requires approximately 15 - 25% travel. Some international travel may be required.


401(k) with company match and Annual Retirement Contribution Plan

Tuition reimbursement Company match of charitable contributions

Health & Wellness programs including onsite flu shots and health screenings

Generous time off for vacation and the option to purchase additional vacation days

Community Outreach Programs

Empowering Our People to Shine

Discover more at

No Phone Calls or Recruiters Please.

This job posting excludes CO applicants.


Date: 05 October 2021              Completed by: Paresh Thakker

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Boston, MA

San Diego, CA

Worker Type


Worker Sub-Type


Time Type

Full time


Save Job

Share This Job





Explore The Area

Related Jobs

View All of Our Available Opportunities

Recently Viewed jobs

No jobs have been viewed recently.

Saved jobs

Sorry, you do not have any saved jobs.

Related Content

Values and Corporate Governance

Explore More

Working Here

Working with us, you will make a positive impact on people’s lives every day - including your own.

Explore More

Global Top Employer 2021

Explore More

Sign up for Job Alerts

Sign up to receive the latest career opportunities directly to your inbox.

First Name

Last Name

Phone Number

Email Address

Interested In

Select a job category from the list of options. Select a location from the list of options. Finally, click “Add” to create your job alert.

Job Category

Select a Job Category

Automation and AI

Business Administration

Business Development

Clinical Development

Communications and Public Affairs

Contingent Workers

Customer Service

Data Sciences

Drug Safety


Environmental Health & Safety

Ethics and Compliance


Human Resources

Information Technology

Insights & Analytics



Manufacturing Sciences


Medical Affairs


Patient and Market Access

Pharmaceutical Sciences

Plasma Management

Process Improvement


Project/Program Management


Real Estate, Facilities, and Security

Regulatory Affairs

Research Science

Sales and Marketing

Strategic Planning

Supply Chain

Therapeutic Area Unit



Select Location

Aktyubinskaya Oblast’, Kazakhstan

Almaty, Kazakhstan

Bács-Kiskun, Hungary

Baden-Württemberg, Germany

Bangkok, Thailand

Baranya, Hungary

Beijing Municipality, China

Bogota D.C., Colombia

Borsod-Abaúj-Zemplén, Hungary

Brandenburg, Germany

Bratislava, Slovakia

Brussels Capital, Belgium

București, Romania

Budapest, Hungary

Buenos Aires F.D., Argentina

Cairo Governorate, Egypt

California, United States

Campeche, Mexico

Canton of Neuchâtel, Switzerland

Canton of Zurich, Switzerland

Capital Region, Denmark

Carinthia, Austria

Central and Western District, Hong Kong SAR

Central District, Israel

Central Java, Indonesia

Csongrád megye, Hungary

Dagestan, Russia

District of Columbia, United States

East Java, Indonesia

East Kalimantan, Indonesia

England, United Kingdom

Georgia, United States

Hajdú-Bihar, Hungary

Harju, Estonia

Hawaii, United States

Henan, China

Heves megye, Hungary

Hlavní město Praha, Czechia

Île-de-France Region, France

Illinois, United States

Istanbul, Turkey

Jakarta Special Capital Region, Indonesia

Jiangsu, China

Kanagawa, Japan

Khabarovsk, Russia

Kyiv City, Ukraine

Land Berlin, Germany

Latium, Italy

Leinster, Ireland

Łódź Voivodeship, Poland

Lower Austria, Austria

Madrid, Spain

Maharashtra, India

Maryland, United States

Massachusetts, United States

Mazovia, Poland

Mecca Region, Saudi Arabia

Metro Manila, Philippines

Mexico City, Mexico

Michigan, United States

Minnesota, United States

Moscow, Russia

National Capital Territory of Delhi, India

New Jersey, United States

New South Wales, Australia

New York, United States

North Holland, Netherlands

North Sumatra, Indonesia

Novosibirsk Oblast, Russia

Nur-Sultan, Kazakhstan

Ohio, United States

Ontario, Canada

Oregon, United States

Ōsaka, Japan

Paraná, Brazil

Penang, Malaysia

Pennsylvania, United States

Pernambuco, Brazil

Riau, Indonesia

Rio de Janeiro, Brazil

Riyadh Region, Saudi Arabia

Salzburg, Austria

San Juan, Puerto Rico

São Paulo, Brazil

Seoul, South Korea

Shanghai Municipality, China

Smolensk Oblast, Russia

South Sulawesi, Indonesia

South Sumatra, Indonesia

St.-Petersburg, Russia

Stockholm County, Sweden

Szabolcs-Szatmár-Bereg, Hungary

Taiwan, Taiwan

Tatarstan Republic, Russia

Texas, United States

Tianjin Municipality, China

Tokyo, Japan

Tuscany, Italy

Tyrol, Austria

Upper Austria, Austria

Uusimaa, Finland

Veneto, Italy

Vienna, Austria

Viken, Norway

Vilnius, Lithuania

Virginia, United States

Volgograd Oblast, Russia

Wallonia, Belgium

Washington, United States

West Java, Indonesia

Yamaguchi, Japan

Yaroslavskaya Oblast’, Russia


Research Science, Boston, Massachusetts, United States


Research Science, San Diego, California, United States



Upload Resume


Confirm Email

By submitting your information, you acknowledge that you have read our applicant privacy notice

and consent to receive email communication from Takeda Pharmaceuticals.


Terms of Use

Privacy Policy

EEO Statement



Job Seekers: Protect yourself against identity theft

Please be aware there are instances of identity thieves posting Takeda-branded jobs and posing as employees to steal personal information. They visit job-related websites and invite candidates to online chats. During the chat, they press job seekers to provide bank account information and Social Security numbers.

At Takeda, we do not ask for personal financial information during telephone, in-person or video interviews. And we are investigating ways to mitigate or stop this scheme. If you have concerns related to this issue, consider the following actions: 1) If in the U.S., place a freeze on your credit reports:;

2) file a complaint with the U.S. Federal Trade Commission:;

and/or 3) file a report with your local police department.

Copyright 1995-2021 Takeda Pharmaceutical Company Limited. All rights reserved.

Connect with us:

Visit us at LinkedIn

Visit us at Twitter

Visit us at Glassdoor

Visit us at YouTube


Company info

Takeda Pharmaceutical Company Limited.
Website :

Similar Jobs:
Patent Attorney (Biotechnology)
Location : Concord, MA
Hamilton Brook Smith & Reynolds, an intellectual property boutique with offices in Boston and Concord, Massachusetts, has a need for a Patent Attorney with a specialty in Biotechnology or a related discipline. Candidates should ha...
$5,000 sign-on bonus based upon eligibility Newly updated pay rates The Chelsea Health Center (CHC) Laboratory is a moderately sized CORE laboratory that focuses on moderate to high complexity testing within CHC- a comprehensive...
Biomedical Engineering Summer 2022 Intern - Undergraduate Location: Minneapolis, Minnesota, United States Requisition #: 21000KPB Post Date: 11 hours ago Careers That Change Lives The possibilities at the intersection of m...
EmploymentCrossing was helpful in getting me a job. Interview calls started flowing in from day one and I got my dream offer soon after.
Jeremy E - Greenville, NC
  • All we do is research jobs.
  • Our team of researchers, programmers, and analysts find you jobs from over 1,000 career pages and other sources
  • Our members get more interviews and jobs than people who use "public job boards"
Shoot for the moon. Even if you miss it, you will land among the stars.
BiotechCrossing - #1 Job Aggregation and Private Job-Opening Research Service — The Most Quality Jobs Anywhere
BiotechCrossing is the first job consolidation service in the employment industry to seek to include every job that exists in the world.
Copyright © 2021 BiotechCrossing - All rights reserved. 168 192