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Biomanufacturing Engineer - Purification Team MSAT Downstream Americas

Company name
Merck Group

Burlington, MA

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A career with MilliporeSigma is an ongoing journey of discovery: our 50,000 people are shaping how the world lives, works and plays through next generation advancements in healthcare, life science and performance materials. For 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others. MilliporeSigma is a business of Merck KGaA, Darmstadt, Germany.

Who we are:

MilliporeSigma is the North American life science brand of Merck KGaA, Darmstadt, Germany – a leading science and technology company. It offers a broad range of innovative products and services to biotech and pharmaceutical drug therapies businesses. Through dedicated collaboration with the scientific and engineering communities, and as one of the top three R&D investors in the life science tools industry, the brand serves as a strategic partner to customers and helps advance the promise of life science.

MilliporeSigma is searching for an Bio Manufacturing Engineer, to join the Purification Team within the Manufacturing Sciences and Technologies Downstream Group. This position serves as a member of a small team (2-4) of technical subject matter experts for MilliporeSigma’s purification technologies, and has a strong Chromatography focus. Based in Billerica, Massachusetts, approximately 20-30% travel in and outside of the US is required.

Your Role:

Serve as a key technical contact for biopharmaceutical customers/clients on critical chromatography purification projects. Provide consultative expertise and technical support for best practices, process development, scale-up and implementation of purification applications. Design experiments and execute experimental protocols with minimal supervision to understand process sensitivity and troubleshoot operational issues. Assess the feasibility and soundness of proposed experiments, materials, or equipment. Critically examine/analyze data and model process behavior to characterize process performance. Recommend scale-up strategies and implementation to Biopharmaceutical customers and clients.

Serve as key interface for Sales, R&D and Marketing Groups for Voice of the Customer and Market Trends. Design and execute reviews/audits to examine process sequence, operation protocol, design parameters and recommend appropriate changes. Keep abreast of the latest development in chromatography technologies including continuous chromatography and linked chromatography processes. Proactively seek out thought leadership opportunities to advance the industry “state of the art”.

Interface with local and international MSAT colleagues to ensure a common Best Practices technical approach for application development and implementation. Recommend continuous improvement in both tools and methodologies. 

Who You Are:

BS/MS in Chemical Engineering with 5 years of experience in related field.

Strong background and practical experience in the purification of proteins & biomolecules.

The candidate will have in depth experience in chromatography unit operations including column packing at pilot and large scale.

Knowledge of the development, scale up and implementation of bioprocess downstream purification technology is an advantage. The candidate will possess a sound knowledge of engineering fundamentals- especially fluid dynamics and an understanding of process economics, and process validation.

Have a demonstrated ability to design experiments and troubleshoot operational issues. Understand scaling issues, constraints and sizing techniques relating to all MilliporeSigma applications.

Possess a current and high level of technical competency in our markets, applications and products.

The candidate must possess an ability to take ownership of complex projects involving diverse groups of individuals. Can produce presentation quality reports in a timely fashion. Possess well-developed verbal, listening and written communication skills and excellent customer facing skills.


Ability to speak Spanish and/or Portuguese a plus

What we offer:

With us, there are always opportunities to break new ground. We empower you to fulfil your ambitions, and our diverse businesses offer various career moves to seek new horizons. We trust you with responsibility early on and support you to draw your own career map that is responsive to your aspirations and priorities in life. Join us and bring your curiosity to life!



Apply and find more information at

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to his/her Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because he/she made a good faith report of discrimination.

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Company info

Merck Group
Website :

Company Profile
Our purpose is to solve the toughest problems in life science by collaborating with the global scientific community – and through that, we aim to accelerate access to better health for people everywhere. We provide scientists and engineers with best-in-class lab materials, technologies and services. With the 2015 combination of Merck Millipore and Sigma-Aldrich, we now have a broad portfolio of 300,000 products, an expanded global footprint and an industry-leading eCommerce platform - We are dedicated to making research and biotech production simpler, faster and safer.

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