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Senior Associate Scientist Protein Expression

Company name
Janssen Research %26 Development, LLC.

Location
Spring House, PA

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Senior Associate Scientist, Protein Expression','1072180510','!*!Janssen Research

and Development, L.L.C., a member of Johnson and Johnson's Family of Companies,

is recruiting for a Senior Associate Scientist, Protein Expression to be in

Spring House, PA. 

 

At

the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters

most is helping people live full and healthy lives. We focus on treating,

curing and preventing some of the most devastating and complex diseases of our

time. And we pursue the most promising science, wherever it might be found.

 

Janssen

Research & Development, LLC discovers and develops innovative medical

solutions to address important unmet medical needs in oncology, immunology,

neuroscience, infectious diseases and vaccines, and cardiovascular and

metabolic diseases.  Please visit http://www.janssenrnd.com/ for more information. 

 

We

are Janssen. Our mission drives us. Our patients inspire us. We collaborate

with the world for the health of everyone in it. Thriving on a diverse company

culture, celebrating the uniqueness of our employees and committed to

inclusion.  Proud to be an equal opportunity employer.

 

The

new Lead Discovery team is a critical part of the Discovery Sciences

organization in Janssen R&D and is committed to the delivery of high

quality chemical leads needed for the generation of small molecule clinical

compounds in all five Janssen Therapeutic Area discovery teams.  This

mission requires deep scientific expertise in a number of disciplines including

chemistry, cellular pharmacology, screening and protein science coupled with an

ability to work collaboratively with internal and external partners.

 

The

Protein Science department within Lead Discovery is responsible for the

delivery of proteins to enable assay development, HTS, pharmacological

profiling and structural biology (X-ray crystallography and NMR).  The

Protein Science Team collaborates closely with Janssen Therapeutic Areas and

functional teams and with external collaborators in academia and

industry.  We seek individuals with a strong ability to connect key stake

holders for the delivery of goals and objectives, fostering an environment of

collaboration, collegiality and positive communication, and who show superior

performance in the context of a multidisciplinary, geographically disperse

team.  The Senior Associate Scientist, Protein Expression will:

Participate in the design and implementation of protein expression

strategies that provide active proteins for use in assays and structural

biologyActively

contribute in protein expression activities including expression optimization

& screening from bench-scale to scale-up utilizing bacterial (E.coli), insect (BEVS),

and mammalian expression systemsAnalyze, interpret, summarize and report experimental dataDevelop innovative approaches to protein expression including

evaluation of new technologiesRemain

current with applicable internal/external scientific literature and apply new

information to successfully complete work assignments. Exhibit

great work ethic and maintain a high level of productivity in the laboratoryCollaborate across multiple therapeutic and functional areas in

the US, Europe and AsiaExhibit strong team spirit: capable of working in a team-based

environment spanning multiple disciplines and

collaborating with scientists and associates in a fast-paced, energetic

environmentBe independent and self-motivated, with a strong sense of urgency

and abilityAttend in-house seminars and external scientific meetings as

appropriate

','!*!B.S./B.A with a minimum

of 7 years of work experience in recombinant protein production OR a Master’s

degree with a minimum of 4 years of work experience in recombinant protein

production is requiredExpertise in the recombinant expression of proteins in insect cell

and mammalian cell lines is requiredExperience in the recombinant expression of proteins in E. coli

bacteria and cell-free systems is preferredExpertise in protein

expression analysis using techniques such as electrophoresis, Western Blot,

flow cytometry, FSEC, protein pull-downs is requiredExperience

working with automated laboratory workflows and instrumentation is

preferredExperience in the analysis of proteins using different

chromatographic techniques such as affinity, ion exchange, hydrophobic

interaction, size exclusion is preferredIndustry experience is preferredExpertise in protein construct design is preferredExperience working with external collaborators in industry or

academia is preferred

','North America-United States-Pennsylvania-Spring House','','Janssen Research & Development, LLC. (6084)','','','Yes, 10 % of the Time','R&D','Senior Associate Scientist, Protein Expression

Company info

Janssen Research %26 Development, LLC.

Company Profile

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