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Principal Scientist - Clinical Biomarker amp Diagnostics

Company name
Amgen, Inc.

San Francisco, CA

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Principal Scientist - Clinical Biomarker & Diagnostics


South San Francisco


Amgen R&D Medical Sciences/Translational Sciences is looking for a Principal Scientist dedicated to biomarker development and implementation within the Clinical Biomarker & Diagnostics (CBD) department of Amgen.

This role is to have specific therapeutic area focus in Cardiometabolic disease. The role of the successful candidate will be to serve as the CBD representative on Amgen's clinical project teams and be responsible for the biomarker strategy for these projects.

The biomarker strategy may include the development or implementation of markers measuring biochemical coverage, pharmacodynamics, patient selection and/or stratification.

The successful candidate is expected to work cross-functionally within Amgen and to interact closely with both the clinical and discovery research groups. The role is responsible for designing experiments, drafting and implementing protocols, executing studies, organizing data, analyzing results, and drafting technical reports or tech transfer documents.

Basic Qualifications:

Doctorate degree and 3 years scientific experience


Master's degree and 6 years of scientific experience


Bachelor's degree and 8 years scientific experience

Preferred Qualifications:

PhD in life sciences and preferably in translational research

Knowledge and experience in cardiovascular and/or metabolic disease

Strong experience in preclinical biomarker discovery/validation and/or implementing biomarker assays in a clinical trial setting

Experience implementing a broad array of platforms and technologies to support a research program

Experience in assay development and qualification and analysis of clinical samples

Ability to focus on key issues and be result oriented

A proven track record of productivity, effective verbal and written communication and interpersonal skills, as well as the ability to work in a team environment

A Fortune 150 company operating in nearly 100 countries around the world, we invest in highly skilled, dedicated and collaborative individuals who are ready to contribute to our mission in meaningful ways and make a difference in the lives of our patients. That's why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Focused on the industry's most compelling scientific discoveries and housed within industry leading facilities within the heart of the world's leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

Company info

Amgen, Inc.
Website :

Company Profile
Amgen discovers, develops, manufactures, and delivers innovative human therapeutics. A leader in biotechnology since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease, and other serious illnesses.

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