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Job Details

Head of Genomics Technologies Group Director

Company name
Takeda Pharmaceuticals U.S.A., Inc.

Location
Cambridge, MA

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Head of Genomics Technologies Group (Director)','1800439','!*!Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda.  Join us as Head Genomics Technologies Group (Director) in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Head Genomics Technologies Group (Director) working on the Translational and Biomarker Research team, you will be empowered to lead the implementation of genomics technologies and manage a group of scientists and a typical day will include: 

 

POSITION OBJECTIVES:

The Translational and Biomarker Research (TBR) group at Takeda designs the clinical biomarker and patient characterization strategies, develops and implements clinical biomarkers assays through a network of external laboratories and delivers high quality biomarker, PK, immunogenicity and patient characterization data to support early and late stage clinical programs and reverse translation.   TBR is dedicated to technical innovation for clinical application across multiple platform types and investigates novel technologies as needed for clinical goals and patient characterization. TBR biomarker strategies and clinical assays are utilized in all therapeutic areas of Takeda’s focus: Neuroscience, Oncology and Gastrointestinal diseases.

We are seeking a senior leader for the genomics technologies group in TBR. This group is responsible for the development and implementation of nucleic acid technology platforms for clinical assays and patient characterization strategies and delivery of high quality data for clinical use and reverse translation.  Working within a completely externally facing model, platform expertise includes DNA and RNA technologies to identify transcriptomic, mutational and epigenetic variations.  Applications range from highly targeted genotyping assays to multiomic longitudinal sequencing studies.  Techniques and methods are tailored to the needs of the clinical trial utilizing nucleic acids from a variety of sources including the tumors, cfDNA, exosomes and the microbiome.  The head of this group will lead a group of scientists to establish high level experimental plans including analysis for genomics assay development and utilization in clinical trials, oversee assay development and outsourcing to vendor labs according to the budget and timelines, deliver high quality data and develop long-term strategy investments in innovative technologies.

 

POSITION ACCOUNTABILITIES:

Direct implementation of genomics technologies in clinical trials for patient characterization and as biomarkers, integrating technical excellence and analytical strategy

Manage a group of scientists to support clinical programs through the development and outsourcing of genomics assays to external vendors, ensure that clinical study timelines for data delivery are met and data is high quality and meets clinical laboratory standards and regulatory and legal requirements

Establish collaborations and effectively communicate TBR genomic capabilities within the global Takeda organizations to advance the use of genomics technologies for forward and reverse translation.

Partner with computational biologists and statisticians to establish priorities for clinical genomics data analysis, management, database build and internal and external supporting resources. Drive identification and use of innovative analytical methods based on clinical data needs

Subject matter expert for clinical application of genomics technologies and analytical tools

Drive technical innovation for patient characterization as platforms evolve and improve','!*!EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:  

PhD in bioinformatics, molecular biology, computational biology or a related field, with 5 years of experience in multiple genomics technologies and applications

Experience with processing and analysis of next-generation sequencing and other genomic data 

Knowledge of genomics applications in multiple disease areas (oncology, neuroscience and gastrointestinal) and able to articulate questions which can be answered from complex data sets

Proven track record of developing strategies and leading the implementation of genomics technologies that are an integral part of drug development and disease characterization

Experience in performing due diligence and implementing innovative technology platforms as part of an overall technology development strategy

Demonstrated ability to establish effective collaborative relationships with cross functional scientific and clinical teams

Strong communication and organizational skills

Supervisory experience

WHAT TAKEDA CAN OFFER YOU:

401(k) with company match and Annual Retirement Contribution Plan

Tuition reimbursement

Company match of charitable contributions

Health & Wellness programs including onsite flu shots and health screenings

Generous time off for vacation and the option to purchase additional vacation days

Community Outreach Programs

Empowering Our People to Shine

Learn more at takedajobs.com.

Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visit http://www.takeda.us/careers/EEO_Policy_Statement.aspx

No Phone Calls or Recruiters Please.

 #LI-MB1','Research and Development','US-MA-Cambridge','','Full-time','Feb 13, 2018','Head of Genomics Technologies Group (Director)

Company info

Takeda Pharmaceuticals U.S.A., Inc.
Website : http://www.takeda.us/

Company Profile
As a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) is among the top 15 pharmaceutical companies in the United States. TPUSA was founded in 1998 to accelerate Takeda's global expansion into the U.S. market. Takeda's U.S. clinical development activities are conducted via Takeda Development Center Americas, Inc., which has a robust pipeline of compounds in multiple therapeutic areas including metabolic and cardiovascular diseases, central nervous system, respiratory and immunology, oncology and general medicine. Striving toward better health is at the center of everything we do. Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, but remains ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine.The spirit of our commitment extends to our employees, partners and the larger community.

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