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Associate Director of Genomics Data Management Boston

Company name
Merck & Co., Inc

Boston, MA

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Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck’s Information Technology organization partners with colleagues across the business to help serve our patients and customers around the world. Ours is a high energy team of dynamic, innovative individuals dedicated to advancing Merck’s contribution to global medical innovation by leveraging information and technology to efficiently advance the business by driving revenue and productivity.

We seek a highly motivated Associate Director to join our Global Research IT team at Merck. As leader of a Genomic Data Management team, the successful candidate will ensure business value is realized from genomic data and analyses associated with Exome, RNA-SEQ, Single Cell RNA, Metagenomics and other types of sequencing. The role will focus on management of end-to-end operations of genomics data management, from acquisition from partners, collaborators and public databases through the delivery of processed biological measurements suitable for translational research into analysis systems.

Job responsibilities will include but are not limited to:

Manage a group of bioinformatics scientists and developers and oversea multiple dimensional genomic data management and operation.

Partner with client service leads in portfolio planning and computing resource planning.

Manage the workflow of data transfer, quality control and data process in collaboration with project management and engineering teams.

Transfer data processing pipelines from research scale into operational services capable of meeting the volume, time and quality requirements of our translational medicine business strategy.

Collaborate with Engineering team to define, improve and co-develop the workflow framework for in-house high performance computing and for cloud-based computing.

Develop and manage protocols for data transfers from external partners and vendors.

Develop next-generation sequencing data quality control metrics including whole exome sequencing, RNA-SEQ, single cell RNA-SEQ and metagenomic sequencing data.

Manage and document data flow and process such as versioning of data process pipelines, metadata and project information.

Integrate public omics and genetics databases to support drug discovery research.



A Bachelors Degree Required.

Master degree or a Ph.D. degree with a focus on computational biology, bioinformatics, or computer science or related fields, or equivalent experience preferred.


A minimum of five years industrial experience for Master degree and two years for Ph.D. degree in large-scale genomic data analysis, integration and management.

A demonstrated track record of leading projects or programs across multiple business organizations.

Ability to drive, operate and executive data management projects effectively.

Extensively experience to use the workflow framework to develop next-generation sequencing data analysis pipelines.

Familiar with next-generation sequencing technology and data flow such as whole genome sequencing, exome sequencing and transcriptome sequencing.

Experience with genome-wide association studies, copy number variation and microarray data analysis.

Proficiency in programming languages (Python, Perl, C, C ) in a Unix/Linux environment.

Experience with high-performance Linux cluster and cloud computing.

Experience of using commercial NGS data management and analysis software.

Excellent oral and written communication skills in English.


Experience in statistics, including familiarity with mathematics and statistics packages such as R.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to

[email protected]

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

Visa sponsorship is not available for this position.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement


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Merck & Co., Inc
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Company Profile
Merck has a long and rich history of working to improve people's health and well-being. Through the years, our researchers have helped to find new ways to treat and prevent illness - from the discovery of vitamin B1, to the first measles vaccine, to cold remedies and antacids, to the first statins to treat high cholesterol. Our scientists also have helped develop many products to improve animal health, including vaccines and antibiotics. /images/merck-history-timeline-screen.jpgWhile we are proud of our past, we are enthusiastic about the future of this new company and we are excited to help create a healthier, brighter future for people around the world.

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