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Sr. Scientist Biologics Discovery Boston

Company name
Merck & Co., Inc

Boston, MA

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Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its

legacy for over a century

. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

We are seeking a highly motivated Senior Scientist with direct, hands-on experience in mammalian expression systems to join the Protein Sciences group in the Biologics Discovery group at MRL Boston. Responsibilities include the expression of antibodies from both recombinant and hybridoma cell lines in transient and stable mammalian cell lines to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.



PhD with a minimum of 2 years of related experience or a MS with a minimum of 4 years of related experience or BS/BA with 7 years of related experience in cell biology, immunology, biochemistry or a related discipline of relevant experience in antibody discovery.


Hands on experience in mammalian cell culture within a BSL-2 environment

Experience in antibody generation in transient transfections of HEK and CHO cells at various scales

Experience in hybridoma cell line development and protein expression

Experience in developing stable cell pools and clones for antibodies

Experience with automated liquid handling system is preferred

Hands-on experience and technical expertise in molecular biology techniques, including PCR, cloning, DNA and RNA purification, SDS-PAGE and Western Blot

Experience with bioreactor systems

Experience with protein purification using automated platforms such as AKTA

Familiarity with key bioinformatics tools

Ability to manage multiple projects simultaneously

Strong written and verbal communication skills

Experience in leading cross functional biologics discovery projects preferred

Experience in the pharmaceutical or biotechnology industry is expected

Preferred :

Experience in antibody engineering and optimization

Experience in supporting biologics programs from target validation to preclinical candidate selection.

Experience with external vendors and collaborators in a fee-for-service and/or co-development capacity

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need an accommodation for the application process please email us at [email protected]

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement


Molecular Discovery - Biologics

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Company info

Merck & Co., Inc
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Company Profile
Merck has a long and rich history of working to improve people's health and well-being. Through the years, our researchers have helped to find new ways to treat and prevent illness - from the discovery of vitamin B1, to the first measles vaccine, to cold remedies and antacids, to the first statins to treat high cholesterol. Our scientists also have helped develop many products to improve animal health, including vaccines and antibiotics. /images/merck-history-timeline-screen.jpgWhile we are proud of our past, we are enthusiastic about the future of this new company and we are excited to help create a healthier, brighter future for people around the world.

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