Merck & Co., Inc
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its
legacy for over a century
. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.
We are seeking a highly motivated Senior Scientist with direct, hands-on experience in mammalian expression systems to join the Protein Sciences group in the Biologics Discovery group at MRL Boston. Responsibilities include the expression of antibodies from both recombinant and hybridoma cell lines in transient and stable mammalian cell lines to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.
PhD with a minimum of 2 years of related experience or a MS with a minimum of 4 years of related experience or BS/BA with 7 years of related experience in cell biology, immunology, biochemistry or a related discipline of relevant experience in antibody discovery.
Hands on experience in mammalian cell culture within a BSL-2 environment
Experience in antibody generation in transient transfections of HEK and CHO cells at various scales
Experience in hybridoma cell line development and protein expression
Experience in developing stable cell pools and clones for antibodies
Experience with automated liquid handling system is preferred
Hands-on experience and technical expertise in molecular biology techniques, including PCR, cloning, DNA and RNA purification, SDS-PAGE and Western Blot
Experience with bioreactor systems
Experience with protein purification using automated platforms such as AKTA
Familiarity with key bioinformatics tools
Ability to manage multiple projects simultaneously
Strong written and verbal communication skills
Experience in leading cross functional biologics discovery projects preferred
Experience in the pharmaceutical or biotechnology industry is expected
Experience in antibody engineering and optimization
Experience in supporting biologics programs from target validation to preclinical candidate selection.
Experience with external vendors and collaborators in a fee-for-service and/or co-development capacity
Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.
If you need an accommodation for the application process please email us at [email protected]
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Molecular Discovery - Biologics
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Merck & Co., Inc
Website : http://www.merck.com
Merck has a long and rich history of working to improve people's health and well-being. Through the years, our researchers have helped to find new ways to treat and prevent illness - from the discovery of vitamin B1, to the first measles vaccine, to cold remedies and antacids, to the first statins to treat high cholesterol. Our scientists also have helped develop many products to improve animal health, including vaccines and antibiotics. /images/merck-history-timeline-screen.jpgWhile we are proud of our past, we are enthusiastic about the future of this new company and we are excited to help create a healthier, brighter future for people around the world.